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SkinMedica

SkinMedica TNS Advanced+ Serum (1 fl. oz.)

A powerful anti-aging serum that targets fine lines, deep wrinkles and sagging skin.

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Image 1 - Image of a skin serum bottle labeled TNS® ADVANCED+ SERUM with a background of glass beakers, featuring the text Next Generation Skin Rejuvenation and additional claims such as Clinically proven to address sagging skin, Smooths visible coarse wrinkles and fine lines, and Results start in just 2 weeks*.
Image 2 - Image showing a side-by-side comparison of a 60-year-old females face before and after using TNS Advanced+ serum, with the Before image on the left showing visible wrinkles and the After image on the right indicating smoother skin with marked improvements at week 2, alongside text detailing baseline and improvements.
Image 3 - Image shows a cream or gel texture with text highlighting key ingredients for skincare. Visible text includes: Key Ingredients TNS-MR An advanced formula to help you get age-defying results with: + NEXT-GENERATION GROWTH FACTOR BLEND Supports healthy skin functions + INNOVATIVE PEPTIDE COMPLEX Nourishes your skin Renessence (RSC) Advanced Specifically designed to support the results of the growth factor blend and includes: + MARINE EXTRACT Supports skin’s renewal process + GREEN MICROALGAE Supports collagen and elastin levels.
Image 4 - A sleek bottle of SkinMedica TNS Advanced+ Serum is displayed next to a small amount of the serum on a light background, with the text stating that in a clinical study, after 12 weeks, patients using the serum felt they looked up to 6 years younger.
Image 5 - A pair of hands holds a cosmetic bottle with instructions on its use, including details on when and how to apply the product, and visible text that reads: How to Use, WHEN TO APPLY, In the morning and evening after cleansing and toning, HOW TO APPLY, Before applying, invert and tap the bottom of the bottle, Remove the cap and press on the center of the pump to dispense onto the back of your hand using a bunny finger application, Blend the product together before applying, Avoid getting in eyes. If contact occurs, rinse eyes thoroughly with warm water.
Image 6 - Image of SkinMedica products arranged on a light background, including an AHA/BHA Exfoliating Cleanser, TNS Advanced+ Serum, Instant Bright Eye Cream, HA⁵ Hydra Collagen Replenish + Restore Hydrator, and Essential Defense Mineral Shield Broad Spectrum SPF 35 Sunscreen, with the text Complete Your SkinMedica Method Routine above them.

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*points earned on final checkout price, after any applied discounts.

Frequently Bought Together

SkinMedica TNS Advanced+ Serum (1 fl. oz.)

This item

SkinMedica TNS Advanced+ Serum (1 fl. oz.)

$295.00

Total Price:

$479.00

Other Customers Bought

Customer Reviews

4.55 stars out of a maximum of 5

5 stars rating 441 reviews

4 stars rating 82 reviews

3 stars rating 32 reviews

2 stars rating 12 reviews

1 stars rating 20 reviews

Top Customer Reviews

Reviews and results may vary from person to person. Customer reviews are and do not represent the views of The Hut Group.

SkinMedica TNS Advanced Serum Improves your skin quality

5 stars out of a maximum of 5

This serum has improved the clarity of my skin and helped minimize wrinkles. I have been getting many complements on my skin since I started using it.

by DianeL Verified Purchase

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Fantastic Serum

5 stars out of a maximum of 5

One of the best serums I have used...application is a breeze & leaves my skin so smooth, erases lines & wrinkles, skin bright & refreshed. Have used the past 2 months & can really tell the difference so will continue to use to improve look & feel. Continual compliments I gladly accept! You will too!!

by SuziQ Verified Purchase

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Super

5 stars out of a maximum of 5

This is by far the best cream I’ve used! Instantly tightens my skin and gives me a smooth appearance! I love love love this!

by Shells Verified Purchase

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Fabulous product

5 stars out of a maximum of 5

I've been using this for about 6 months and combined w/the HA my skin is really looking much more youthful.

by Skincare aficionado Verified Purchase

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effective

5 stars out of a maximum of 5

This serum has not only improved the signs of aging on my face it has held further aging at bay. preventative

by jannil Verified Purchase

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Doesn’t irritate my skin

5 stars out of a maximum of 5

My skin is very sensitive and this does not irritate my skin. It leaves my face feeling very smooth and my skin is glowing again. I wish it weren’t so expensive.

by Mk Verified Purchase

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I used to love it

1 stars out of a maximum of 5

I’ve used the TNS Serum for years and this is the second container I’ve had that doesn’t dispense from both sides. The first one DERMSTORE wouldn’t exchange because I didn’t have the original container - I tend to stock up when it’s on sale. I just opened a new one from Black Friday sale and once again, it’s faulty!

by MD Verified Purchase

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Amazing

5 stars out of a maximum of 5

I’ve only been using this serum for about a month and have already seen results. My pores are noticeably smaller and the surface level texture is much smoother. My smile lines are plumper and more resilient to movement. My only critique is the pump tends to dispense unevenly. To get around this, store the bottle upside down and use two fingers on the pump (one on each side).

by DS Verified Purchase

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I want to love this product.

3 stars out of a maximum of 5

I switched back to TNS Advanced after seven years of using another product line. I thought it would say me money. Instead of using multiple products I could use one or two. I want to love the product but I'm not sure It will work to its full potential because it only dispenses the product from one side. I would like to return but have thrown away the packaging. It's a too expensive for faulty packaging. I will see how it works.

by Annette Verified Purchase

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Great Product, Bad Inventory

4 stars out of a maximum of 5

The serum itself is great but in order to benefit from the serum, you need to have a functional bottle/ dispenser for it. I had a subscription for over 2 years and purchased a bottle every other month. Several of the bottles only dispensed on one side or the other, which negates the effectiveness of the serum. Dermstore does not replace or warrant the faulty bottles so if you have the poor luck of receiving a defective item, you are just out $250+. Also, many of the bottles were dated from 2022 (in 2023 & 2024) so I am not sure of the shelf life either. Perhaps I will have better luck ordering directly from Skinmedica.

by Amanda P Verified Purchase

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