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Microbiome Enzyme Essence

$82

Our next-generation prebiotic essence is clinically proven to deliver plump, dewy looking skin. It's like gut health, but for your skin!

Size Full Size (4oz | 118mL)

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Clinical Results

93% said their skin is healthier-looking*

90% said their skin looks dewy after using this product*

86% said their skin feels baby soft*

*Based on a 28-day clinical study of 35 women aged 25-65, twice daily use

How to Use

Nourishing Cleansers & Toners

Anti-Aging Treatments

Regenerative Face Oils

Advanced
Eye Treatments

Strengthening Moisturizers

After cleansing, pour 2-3 shakes in the palms of hands and gently press and pat into face and neck. Use in the morning and in the evening as needed.

What It Is

This clinically proven essence floods the skin with the highest quality hydrating botanicals and active prebiotics that nourish your skin’s good bacteria to reveal baby soft, dewy and illuminated skin every single day. A healthy skin microbiome helps strengthen your skin barrier, protect skin from irritants and inflammation, and helps to improve your skin’s nutrient absorption. Our Microbiome Enzyme Essence delivers on those benefits while also providing resurfacing benefits with nature’s most gentle yet effective AHAs and enzymes like wild-sourced Finger Lime and biocompatible Papaya & Pineapple. Use this essence to prep your skin for the next steps in your routine all while you strengthen & protect it, too. Winner of the 2023 SELF Healthy Beauty Award for Best Essence.

Key Ingredients

Pineapple & Papaya Enzyme

Pineapple & Papaya Enzyme

Our Pineapple & Papaya Enzymes work to soften and naturally exfoliate by shedding the dead skin layer on the surface of the skin.
Wild-Sourced Finger Lime

Wild-Sourced Finger Lime

Rich in AHAs (Alpha Hydroxy Acids), Finger Lime helps to break down dead skin cells and shed the outermost layer of dry skin, allowing the epidermis to increase absorption of water and emollients.
Buckwheat Ferment

Buckwheat Ferment

Our Buckwheat Ferment is a fermented prebiotic that helps to balance, support and nourish the skin's microbiome.

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FAQs

Can I use this with Clear Toner?

Yes! After applying Clear Toner, you can apply our Microbiome Enzyme Essence. The two of them work better together!

Is this good for all skin types?

Yes, all skin types can benefit from the Microbiome Enzyme Essence, especially dry skin types. It’s also great for sensitive skin types!

Is this product safe to use during pregnancy?

Yes! Our Microbiome Enzyme Essence is MADE SAFE® Certified, which ensures it is free from over 15,000 known toxins and has undergone further rigorous testing to ensure it does not contain any ingredients known to or suspected of harming pregnant individuals. If you are pregnant or breastfeeding, we always recommend consulting with your doctor before introducing any new skincare products into your routine. Everyone's skin and situation is different, so we cannot take into account your unique needs that may contribute to differentiated standards during your pregnancy or postpartum period. For more information, check the MADE SAFE® Healthy Pregnancy Guide.

How long will the Microbiome Enzyme Essence last?

Each bottle contains approximately 236 uses. When used twice daily, it will last about 118 days. If used once a day, it will last double the time - 236 days. Your usage may vary depending on how much you apply.

Pure. Potent. Proven.®

Luxurious, aromatherapeutic products formulated with the purest, functional plant actives that fill your skin's nutrient gaps, support your skin's microbiome, and deliver clinically proven results. This is a better path to anti-aging.

Learn More

05/10/25

Alysha P.

12/30/24

Best skincare products I’ve used in a long time

It doesn’t take long to see and feel results. My skins looks brand new every time I do my routine. The quality is there and it’s clear.

Image of Review by Alysha P. on 30 Dec 2024 number 1

On http://truebotanicals.com

Olga J.

12/11/24

Incredible products

I own 14 products - from oils, to moisturizers, to masks and serums, for face, lips, and body - they're all incredible to protect my dry skin in the cold weather. I finally found my brand

Image of Review by Olga J. on 11 Dec 2024 number 1

jen

07/27/24

Perfection

I’m so excited to have discovered this brand. The products, service and shipping have all been phenomenal! My skin is finally fully hydrated and looks years younger, I will be a loyal customer.

Image of Review by jen on 27 Jul 2024 number 1

Lisa K.

05/26/24

My collection

I love every product! I feel my skin is healthier and more radiant

Image of Review by Lisa K. on 26 May 2024 number 1

Jennifer P.

04/26/24

I love this line!

I am two years into solely using True Botanicals. I’m almost 51 years-old and I can’t tell how many people are shocked when I tell them my age.
I love both eye creams and they have done wonders for my dark circles.

Image of Review by Jennifer P. on 26 Apr 2024 number 1

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Microbiome Enzyme Essence

Clinical Results